The disease described by Dupuytren is due to a change in the fibrous layer of the palm and of the fingers.
It occurs in people suffering from diseases that can promote its appearance (diabetes, lung diseases). Also there are families in which the disease is transmitted by heredity.
Dupuytren's contracture is manifested by the formation of nodules and thickening situated in and on the palmar surface of the fingers. In some cases the disease remains stable for years without shrinkage. Most often however, the retractile properties of the disease are manifested by a progressive bending of the fingers.
This progression might occur over several months or it may take years. All the fingers can be affected but it is the ring finger and the little finger which are the most frequently affected.
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